Table 6.

Summary of preliminary treat-to-target recommendations.

1A state of clear or almost clear skin should be a therapeutic target for psoriasis regardless of the area affected (e.g., nails, scalp, soles, palms, trunk, extremities, etc.) and the duration of disease (early vs late disease).
2Because a state of remission may be difficult to reach in psoriatic arthritis, a state of minimal disease activity is an acceptable therapeutic target.
3Quality of life is an important outcome from the patient and physician perspective and should be included in therapeutic targets.
4Functional impairment, comorbidities, and treatment risks should be considered when making clinical decisions in addition to assessing measures of disease activity.
5Physicians and patients must be in agreement regarding selected therapeutic targets, taking into consideration initial severity of disease and the appropriate time frame to reach this target.
6Patients must be treated adequately to reach the selected therapeutic targets, with therapy adjustments every 3 months for patients with active disease and every 6 to 12 months for those with stable disease (when therapeutic targets are reached).
7Once reached, the state of clear or almost clear skin should be maintained for as long as possible with adjustment in therapy at the first signs of disease progression.
8Standard safety assessments should be performed at each visit.