Table 2.

Change from baseline to Week 36. Values are means (standard errors) adjusted for baseline outcome and body mass index.

Change from Baseline to Week 36MIACp
Improvement in SF-36 physical function
  Opioid users10.25 (1.94)7.00 (1.87)0.234
  Opioid nonusers14.47 (1.23)9.66 (1.22)0.006*
Reduction in BPI pain severity
  Opioid users−0.80 (0.17)−0.76 (0.16)0.930
  Opioid nonusers−1.49 (0.12)−0.98 (0.12)0.004*
Improvement in global FM severity, FIQ total
  Opioid users−9.60 (1.71)−9.49 (1.66)0.963
  Opioid nonusers−15.47 (1.21)−11.85 (1.20)0.036*
Increase in LMPA**
  Opioid users3.64 (0.84)3.26 (0.82)0.746
  Opioid nonusers4.68 (0.52)3.01 (0.51)0.023*
  • * p < 0.05; analyses included subjects (n = 198, 92% of 216) with 6-month followup data.

  • ** No. hours per week. MI: motivational interviewing; AC: attention control; SF-36: Medical Outcomes Study Short Form-36; BPI: Brief Pain Inventory; FM: fibromyalgia; FIQ: Fibromyalgia Impact Questionnaire; LMPA: light to moderate physical activity.