The proportion of patients with recurrent gout, increased risk of flares, and flares per gout flare patient, according to SUA level.
| Study | Period of Flare Measure, Yrs | SUA Level Category, mg/dl | Patients with Flares | Flares per Gout Flare Patient, Mean (SD) | |
|---|---|---|---|---|---|
| % | Ratio of % | ||||
| Estimates from clinically confirmed gout studies | |||||
| Perez-Ruiz, et al22 | 4.6 (mean) | ≥ 6.0 to < 7.0 | 3.7 | Referent | — |
| ≥ 7.0 to < 8.2 | 21.3 | 5.8 | — | ||
| ≥ 8.3 to < 9.3 | 50.8 | 13.7 | — | ||
| ≥ 9.3 | 61.3 | 16.6 | — | ||
| Shoji, et al23 | > 1 | < 6.0 | 12.0 | Referent | — |
| ≥ 6.0 to < 9.0 | 47.7 | 4.0 | — | ||
| ≥ 9.0 | 89.5 | 7.5 | — | ||
| Estimates from retrospective database studies | |||||
| Halpern, et al34 | 2 | < 6.0 | 46.4 | Referent | 1.3 (0.6) |
| ≥ 6.0 to < 9.0 | 61.2 | 1.3 | 1.5 (0.8) | ||
| ≥ 9.0 | 63.8 | 1.4 | 1.7 (1.0) | ||
| Sarawate, et al35 | 5 | < 6.0 | 23.0 | Referent | — |
| ≥ 6.0 to < 8.0 | 33.0 | 1.4 | — | ||
| ≥ 8.0 | 45.0 | 2.0 | — | ||
| Wu, et al36 | 1 | < 6.0 | 26.9 | Referent | 1.5 (0.8) |
| ≥ 6.0 to < 9.0 | 43.4 | 1.6 | 1.6 (0.9) | ||
| ≥ 9.0 | 54.5 | 2.0 | 1.7 (1.2) | ||
SUA: serum uric acid.