Characteristics | Histopathological Classes | p* | |||
---|---|---|---|---|---|
Focal, n = 46 | Crescentic, n = 36 | Sclerotic, n = 36 | Mixed, n = 68 | ||
Renal involvement, median (range) | |||||
Serum creatinine, μmol/l | 93 (42–620) | 383 (60–1363) | 432.5 (91–952) | 231 (44–1096) | < 0.001 |
eGFR, ml/min × 1.73m2 | 72 (5.6–156.4) | 11.2 (3.0–134.7) | 9.8 (3.3–74.7) | 20.6 (3.6–156.3) | < 0.001 |
Proteinuria, mg/day | 446.0 (60–9806) | 1514 (125–6720) | 1916 (179–5729) | 1292(160–8957) | 0.002 |
Glomerular injury, %, mean ± SD | |||||
Normal | 75.8 ± 15.5 | 9.0 ± 11.8 | 6.7 ± 10.4 | 14.6 ± 16.1 | < 0.001 |
Cellular crescents | 4.8 ± 7.5 | 63.8 ± 10.7 | 8.2 ± 15.7 | 19.1 ± 15.8 | < 0.001 |
Tubulointerstitial injury, n | < 0.001 | ||||
Score 0 | 6 | 4 | 0 | 0 | |
Score 1 | 34 | 20 | 3 | 35 | |
Score 2 | 4 | 9 | 8 | 20 | |
Score 3 | 2 | 3 | 25 | 13 |
↵* p value applies to the variable across the differing histological classes. eGFR: estimated glomerular filtration rate.