Multivariate analysis for relapse.
| Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|
| sHR (95% CI) | p | sHR (95% CI) | p | |
| Creatinine ≤ 100 μmol/l | 1 | NA | 1 | NA |
| 100 < Creatinine ≤ 300 | 0.79 (0.50–1.25) | 0.32 | 0.71 (0.44–1.14) | 0.16 |
| Creatinine > 300 μmol/l | 0.42 (0.22–0.82) | 0.01 | 0.33 (0.17–0.65) | < 0.01 |
| Skin involvement | 1.81 (1.04–3.15) | 0.03 | ||
| Kidney involvement | 0.65 (0.44–0.95) | 0.03 | ||
| Country: Japan | 0.49 (0.32–0.76) | < 0.01 | 0.39 (0.24–0.64) | < 0.01 |
Subdistribution hazard ratios (sHR), 95% CI, and p values were calculated by competing risk model for the combined population of Addenbrooke’s Hospital and the 14 Japanese hospitals (n = 210). NA: not applicable; creatinine: serum creatinine levels.