Organ involvement. Data are n (%).
| UK, n = 128 | Japan, n = 82 | p | |
|---|---|---|---|
| General | 106 (82.8) | 58 (70.1) | 0.04 |
| Skin | 19 (14.8) | 10 (12.2) | 0.59 |
| Eye, mucosa | 32 (25.0) | 34 (41.5) | 0.01 |
| ENT | 105 (82.0) | 72 (87.8) | 0.26 |
| Heart | 3 (2.3) | 1 (1.2) | 1.00 |
| Nerve | 29 (22.7) | 13 (15.9) | 0.23 |
| Peripheral nerve | 22 (17.2) | 10 (12.2) | 0.33 |
| Central nerve | 8 (6.3) | 4 (4.9) | 0.77 |
| Intestine | 2 (2.7) | 3 (3.7) | 0.38 |
| Kidney | 61 (47.7) | 42 (51.2) | 0.61 |
| Respiratory | 52 (40.6) | 57 (69.5) | < 0.01 |
| IP/fibrosis | 6 (4.7) | 17 (20.7) | < 0.01 |
| Nodule/tumor/cavity | 36 (28.1) | 46 (56.1) | < 0.01 |
| AH | 15 (11.7) | 5 (6.1) | 0.23 |
| Others* | 4 (3.1) | 3 (3.7) |
↵* In the United Kingdom, included temporal arteritis, splenic infarction, pancreatitis, and orchitis. In Japan, included aortitis, necrotizing lymphadenitis, and prostatitis. P value was calculated by the chi-square test comparing United Kingdom and Japan. In those analyses where the expected frequency was < 5 in 1 or more cells, the p value was calculated by Fisher’s exact test. IP/fibrosis: interstitial pneumonia/pulmonary fibrosis; AH: alveolar hemorrhage; ENT: ear, nose, and throat.