Uni- and multivariable linear regressions exploring the effect of radiographic damage on physical functioning and health-related quality of life, measured with HAQ-DI and SF-36 PCS.
| HAQ-DI | SF-36 PCS | |||||||
|---|---|---|---|---|---|---|---|---|
| Univariable Analysis | Multivariable Analysis | Univariable Analysis | Multivariable Analysis | |||||
| β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
| Erosion score, per 10 points worsening* | 0.51 (0.10–0.91) | 0.015 | 0.47 (0.09–0.84) | 0.015 | −2.02 (−10.28 to 6.22) | 0.63 | −1.44 (−9.46 to 6.58) | 0.72 |
| JSN score, per 10 points worsening* | 0.02 (−0.43 to 0.46) | 0.94 | −0.09 (−0.32 to 0.49) | 0.68 | 4.08 (−4.64 to 12.80) | 0.36 | 3.03 (−5.39 to 11.44) | 0.48 |
| R2 model, % | 26 | 14 | ||||||
| Variance (R2) explained by radiographic damage scores, % | ||||||||
| Erosion | 6.0 | 0.2 | ||||||
| JSN | 0.2 | 0.6 | ||||||
↵* Tested separately in multivariable analysis. Multivariable analyses adjusted for age, sex, disease duration, and comorbidity (calculated by the Rheumatic Diseases Comorbidity Index). HAQ-DI: Health Assessment Questionnaire–Disability Index; SF-36 PCS: Medical Outcomes Study Short Form-36 questionnaire physical component score; JSN: joint space narrowing.