Myopathological markers of muscle biopsies slides. Values are n (%).
| Characteristics | n | SSc-PM, n = 24 |
|---|---|---|
| Necrotic muscle fibers | 24 | 23 (96) |
| Lymphocytic infiltrates | 24 | 15 (63) |
| Positive MHC class I staining | 12 | 11 (92) |
| Inflammation* | 24 | 19 (79) |
| MAC staining | 10 | 5 (50) |
| Fibrosis | 19 | 5 (26) |
| Presence of COX-negative fibers | 10 | 3 (30) |
| Presence of CD8-positive T cells | 12 | 8 (67) |
↵* Inflammation is defined as positive MHC class I staining or/and presence of lymphocytic infiltrates. SSc: systemic sclerosis; PM: polymyositis; MAC: membrane attack complex; COX: cytochrome oxidase.