Reproducibility measures.
| Author | Participants | Reproducibility Feature | Findings |
|---|---|---|---|
| Bone microarchitecture measures | |||
| Kleyer17 | ACPA + but no history of arthritis and no signs of arthritis (n = 15); ACPA– (n = 15) | Interrater | ICC > 0.90 |
| Kleyer17 | ACPA+ but no history of arthritis and no signs of arthritis (n = 15); ACPA– (n = 15) | Intrarater | ICC > 0.95 |
| Fouque-Aubert46 | RA (n = 93); control (n = 43) | Repositioning and scan/rescan | CV 2.9–12.5% |
| Feehan30 | Healthy (n = 10) | Scan/rescan | ICC > 0.884, CV < 4.8%, RMSCV < 6.2% |
| Barnabe27 | RA (n = 15); control (n = 15) | Contouring reproducibility* | RMSCV < 0.8% |
| Bone mineral density | |||
| Töpfer23 | RA (n = 18) | Interrater | RMSCV < 3.1% |
| Töpfer23 | RA (n = 18) | Intrarater | RMSCV < 3.3% |
| Feehan30 | Healthy (n = 10) | Scan/rescan | ICC > 0.975, CV < 1.5%, RMSCV < 2.1% |
| Fouque-Aubert46 | RA (n = 93); control (n = 43) | Repositioning and scan/rescan | CV < 1.8% |
| Barnabe27 | RA (n = 15); control (n = 15) | Contouring reproducibility* | RMSCV < 0.8% |
| Cortical break count | |||
| Simon21 | PsO (n = 56); healthy (n = 24) | Interrater | r = 0.96 |
| Scharmga18 | Unknown history/cadaver (n = 8) | Intrarater | ICC 0.399 |
| Simon21 | PsO (n = 56); healthy (n = 24) | Intrarater | r = 0.98 |
| Erosion detection | |||
| Barnabe11 | RA and controls (n = 58 joints) | Interrater | Agreement 90.2% |
| Barnabe13 | RA (n = 9) | Interrater | Agreement 92.9%; κ= 0.711, 95% CI 0.539–0.839 |
| Regensburger7 | RA (n = 103) | Interrater | κ = 0.975 |
| Erosion count | |||
| Albrecht24 | RA (n = 50) | Interrater | ICC range 0.936–1.00 |
| Hecht16 | RA (n = 267) | Interrater | ICC range 0.872–1.000 |
| Regensburger7 | RA (n = 103) | Interrater | ICC 0.979 (95% CI 0.976–0.982) |
| Scharmga18 | Unknown history/cadaver (n = 8) | Intrarater | ICC 0.142 |
| Aschenberg25 | RA (n = 40) | Interrater* | ICC mean 0.79; range 0.57–0.95 |
| Erosion size | |||
| Barnabe11 | RA and controls (n = 58 joints) | Interrater | RMSCV range 12.3–24% |
| Barnabe13 | RA (n = 9) | Interrater | RMSCV range 15.7–36.4% |
| Finzel33 | RA (n = 20) | Interrater | ICC > 0.93 |
| Finzel45 | RA (n = 51) | Interrater | ICC 0.95 |
| Srikhum35 | RA (n = 16); healthy (n = 7, all MCP, n = 3 wrist) | Interrater | ICC 0.89, RMSE 9.4% |
| Töpfer9 | RA (n = 22) | Interrater | Precision error range 6.0–8.3% |
| Finzel33 | RA (n = 20) | Intrarater | ICC 0.99 |
| Finzel45 | RA (n = 51) | Intrarater | ICC 1.0 |
| Srikhum35 | RA (n = 16); healthy (n = 7 all MCP, n = 3 wrist) | Intrarater | ICC 0.99, RMSE 4.7% |
| Erosion score | |||
| Stach48 | RA (n = 58); control (n = 30) | Interrater | κ= 0.75 |
| Aschenberg25 | RA (n = 40) | Interrater* | ICC mean 0.79; range 0.57–0.95 |
| Stach48 | RA (n = 58); control (n = 30) | Intrarater | κ = 0.82 |
| Erosion sphericity | |||
| Töpfer23 | RA (n = 18) | Interrater | RMSCV 5.5% |
| Toepfer40 | RA (n = 18) | Interrater | RMSCV 4.9% |
| Töpfer23 | RA (n = 18) | Intrarater | RMSCV 2.8% |
| Toepfer36 | RA (n = 25) | Intrarater | RMSCV 2.5% |
| Erosion surface area | |||
| Töpfer23 | RA (n = 18) | Interrater | RMSCV 9.9% |
| Toepfer40 | RA (n = 18) | Interrater | RMSCV 10.4% |
| Töpfer23 | RA (n = 18) | Intrarater | RMSCV 5.8% |
| Toepfer36 | RA (n = 25) | Intrarater | RMSCV 4.7% |
| Erosion volume | |||
| Regensburger7 | RA (n = 103) | Interrater | ICC 0.951 (95% CI 0.937, 0.962) |
| Töpfer23 | RA (n = 18) | Interrater | RMSCV 7.8% |
| Toepfer40 | RA (n = 18) | Interrater | RMSCV 7.8% |
| Töpfer23 | RA (n = 18) | Intrarater | RMSCV 5.7% |
| Toepfer36 | RA (n = 25) | Intrarater | RMSCV 4.1% |
| Joint space width | |||
| Barnabe27 | RA (n = 15); control (n = 15) | Contouring reproducibility | RMSCV 17.1% |
| Barnabe26 | ERA (n = 10) | Repositioning | RMSCV 4.8% |
| Boutroy28 | Healthy (n = 6) | Repositioning | Estimates vary with positioning at 0° and 30°; maximum increases 12.5% and mean increases 16.4%, less effect on volume, minimum, and asymmetry |
| Burghardt29 | RA (n = 16); control (n = 7) | Scan/re-scan | RMSCV range 2.1–13.9% |
| Osteophyte measurement | |||
| Finzel34 | PsA (n = 41); RA (n = 43) | Interrater | r = 0.9692 |
| Finzel34 | PsA (n = 41); RA (n = 43) | Intrarater | r = 0.9722 |
| Osteophyte count | |||
| Aschenberg25 | RA (n = 40) | Interrater* (osteophyte count) | ICC mean 0.79; range 0.57–0.95 |
| Osteophyte score | |||
| Aschenberg25 | RA (n = 40) | Interrater* (osteophyte score) | ICC mean 0.79; range 0.57–0.95 |
↵* In each article, results were not separated for the different measures. PsA: psoriatic arthritis; RA: rheumatoid arthritis; BMD: bone mineral density; EIA: early inflammatory arthritis; ACPA: anticitrullinated protein antibodies; PsO: psoriasis; RF: rheumatoid factor; RMSCV: root mean square coefficient of variation; ICC: intraclass correlation coefficients; MCP: metacarpophalangeal joint; RMSE: root mean square error; ERA: early RA.