Table 3.

MCII/PASS for BASDAI/BASFI restricted to patients with baseline BASDAI ≥ 4. Numbers of the strata will not always add up to the total number of patients owing to missing values in the variable according to which patients are stratified.

VariablesBASDAIBASFI
PASSMCIIPASSMCII
nValue (95% CI)nValue (95% CI)nValue (95% CI)nValue (95% CI)
Patients with baseline BASDAI ≥ 4, n = 1771154.5 (4.2–4.8)881.1 (0.8–1.4)1034.6 (4.2–5.0)730.6 (0.3–0.9)
Women264.3 (3.5–5.1)231.2 (0.6–1.8)224.2 (3.2–5.2)200.6 (0.0–1.2)
Men884.6 (4.2–5.0)651.0 (0.6–1.4)804.6 (4.2–5.0)520.5 (0.1–0.9)
HLA-B27+754.6 (4.2–5.0)541.0 (0.6–1.4)694.7 (4.1–5.3)400.5 (0.1–0.9)
HLA-B27−174.5 (3.5–5.5)221.1 (0.3–1.9)143.6 (2.4–4.8)121.0 (0.2–1.8)
Age ≤ 41.4 yrs484.4 (4.0–4.8)390.9 (0.5–1.3)403.3 (2.7–3.9)370.8 (0.4–1.2)
Age > 41.4 yrs604.8 (4.4–5.2)481.1 (0.7–1.5)575.3 (4.7–5.9)350.3 (0.0–0.7)
SpA-EAM history, yes434.5 (3.9–5.1)311.1 (0.7–1.5)404.6 (4.0–5.2)250.7 (0.3–1.1)
SpA-EAM history, no664.7 (4.3–5.1)520.8 (0.4–1.2)584.8 (4.2–5.4)420.5 (0.1–0.9)
Disease duration ≤ 11 yrs504.0 (3.4–4.6)391.2 (0.6–1.8)503.7 (3.1–4.3)380.7 (0.3–1.1)
Disease duration > 11 yrs594.8 (4.4–5.2)440.8 (0.4–1.2)495.4 (4.8–6.0)310.5 (0.1–0.9)
  • MCII: minimum clinically important improvement; PASS: patient-acceptable symptom state; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; SpA-EAM: spondyloarthritis extraarticular manifestations.