Table 6.

Univariate and multivariate predictors of remission after 1 and 3 years. Data are OR (95% CI) except for Nagelkerke R².

Variables	Year 1, n = 198		Year 3, n = 149
Variables	DAS28	SDAI	DAS28	SDAI
Univariate
Adherence level (≥ 80% vs < 80%)	3.70 (1.96–6.97)^*	4.85 (2.10–11.23)^*	6.87 (3.21–14.66)^*	7.31 (2.78–19.19)^*
Modified adherence (10% increment)	1.26 (1.03–1.54)^*	1.22 (0.97–1.54)	1.57 (1.26–1.95)^*	1.75 (1.35–2.27)^*
Multivariate
Adherence level (≥ 80% vs < 80%)	1.81 (0.57–5.70)	3.06 (0.76–12.41)	5.08 (1.67–15.45)^*	10.37 (1.94–55.49)^*
Modified adherence (10% increment)	1.14 (0.83–1.56)	1.00 (0.67–1.36)	1.45 (1.06–1.98)^*	1.49 (0.99–2.25)
Nagelkerke R²	0.446	0.384	0.447	0.514

↵* p < 0.05. Multivariate analysis was controlled for baseline DAS28, BMI, smoking status, PGA, physical function, helplessness, pain, fatigue, weeks to dose escalation, frequency of clinic visits, addition of further DMARD, and existence of significant toxicity (yes/no). DAS28: Disease Activity Score in 28 joints; SDAI: Simplified Disease Activity Index; BMI: body mass index; PGA: physician’s global assessment; DMARD: disease-modifying antirheumatic drug.