Table 1.

Studies included in the systematic review.

Author, yearRefParticipantsType of StudyJoints IncludedOutcomesType of Publication
Lee, 20156RA (n = 16)CohortWrist, MCP2–3Erosions, other radiographyFull-length report
Regensburger, 20157RA (n = 103)Cross-sectionalMCP2–3Erosions, other radiography, reproducibilityFull-length report
Tom, 20158EIA (n = 47)CohortMCP2–3 BMA,BMD, erosions, joint space, other radiographyAbstract
Töpfer, 20159RA (n = 22)CohortMCP2–4BMA, BMD, erosions, reproducibilityFull-length report
Yang, 201510RA (n = 12); control (n = 6)Cross-sectionalMCP2–3BMA, BMDFull-length report
Barnabe, 201411RA and controls, n = 58 jointsCross-sectionalMCP2–3Erosions, reproducibilityAbstract
Barnabe, 201412Cadaver (n = 6)Cross-sectionalMCP2–3Joint spaceAbstract
Barnabe, 201413RA (n = 9)CohortMCP2–3Erosions, reproducibilityAbstract
Finzel, 201414PsA (n = 25); OA (n = 25)Cross-sectionalMCP2–4Osteophytes, reproducibilityFull-length report
Haschka, 201415ERA (n = 10); control (n = 10)Cross-sectionalMCP2Vessel channelsAbstract
Hecht, 201416RA (n = 267)Cross-sectionalMCP2–4Erosions, reproducibilityFull-length report
Kleyer, 201417ACPA+ but no history of arthritis and no signs of arthritis (n = 15); ACPA– (n = 15)Cross-sectionalMCP2–4BMA, BMD, erosions, cortical breaksFull-length report
Scharmga, 201418Unknown history/cadaver (n = 8)Cross-sectionalMCP (not specified)Erosions, cortical breaks, other radiography, reproducibilityAbstract
Simon, 201419PsO (n = 55); control (n = 47)Cross-sectionalMCP2–3Erosions, osteophytesAbstract
Simon, 201420PsO (n = 55)Cross-sectionalMCP2–3Erosions, osteophytes, other radiographyAbstract
Simon, 201421PsO (n = 56); healthy (n = 24)Cross-sectionalMCP2Vessel channels, reproducibilityAbstract
Teruel, 201422RA (n = 16)Cross-sectionalWristOther radiographyFull-length report
Töpfer, 201423RA (n = 18)Cross-sectionalMCP2–4Erosions, reproducibilityFull-length report
Albrecht, 201324RA (n = 50)Cross-sectionalMCP2–4Erosions, other radiography, reproducibilityFull-length report
Aschenberg, 201325RA (n = 40)CohortMCP2–3Erosions, osteophytes, reproducibilityFull-length report
Barnabe, 201326ERA (n = 10)Cross-sectionalMCP2–3Joint space, reproducibilityAbstract
Barnabe, 201327RA (n = 15); control (n = 15)Cross-sectional jointMCP2–5 for space, MCP2–3 for BMA and BMDBMA, BMD, erosions, joint space, other radiography, reproducibilityFull-length report
Boutroy, 201328Healthy (n = 6)Cross-sectionalMCP2Joint space, reproducibilityAbstract
Burghardt, 201329RA (n = 16); control (n = 7)Cross-sectionalMCP2–4Joint space, other radiography, reproducibilityFull-length report
Feehan, 201330Healthy (n = 10)CohortMCP2–3BMA, BMD, reproducibilityFull-length report
Finzel, 201331RA (n = 27); control (n = 20)Cross-sectionalWristCortical breaks, erosions, other radiographyAbstract
Finzel, 201332RA (n = 27);
Finzel, 201333RA (n = 20)CohortMCP2–4Erosions, reproducibilityFull-length report
Finzel, 201334PsA (n = 41); RA (n = 43)CohortMCP2–4Erosions, osteophytes, reproducibilityFull-length report
Srikhum, 201335RA (n = 16), healthy (n = 7 all MCP, n = 3 wrist)Cross-sectionalWrist, MCP2–3Erosions, other radiography, reproducibilityFull-length report
Toepfer, 201336RA (n = 25)Cross-sectionalMCP2–4Erosions, reproducibilityAbstract
Toepfer, 201337RA (n = 17)CohortMCP2–4Erosions, BMDAbstract
Williams, 201338Unknown history/cadaver (n = 5)Cross-sectionalMCP (also PIP and DIP, data not separated out)Cortical breaks, other radiographyAbstract
Zhu, 201339RA (n = 56); control (n = 56)Cross-sectionalMCP2BMA, BMDAbstract
Toepfer, 201240RA (n = 18)Cross-sectionalMCP2–4Erosions, reproducibilityAbstract
Finzel, 201141RA (n = 26); control (n = 17)Cross-sectionalMCP2–5Cortical breaks, other radiography, erosionsAbstract
Finzel, 201142PsA (n = 30); RA (n = 58)Cross-sectionalMCP2–4Erosions, osteophytes, vessel channels, surface changesFull-length report
Finzel, 201143RA (n = 25); PsA (n = 25); EHOA (n = 25)Cross-sectionalMCP2–4Erosions, joint spaceAbstract
Finzel, 201144RA (n = 14); PsA (n = 6); control (n = 6)Cross-sectionalMCP2–4Erosions, other radiographyFull-length report
Finzel, 201145RA (n = 51)CohortMCP2–4Erosions, reproducibilityFull-length report
Fouque-Aubert, 201046RA (n = 93); control (n = 43)Cross-sectionalMCP2–3BMA, BMD, erosions, other radiography, reproducibilityFull-length report
Kolling, 201047Healthy (n = 19)Cross-sectionalMCPBMA, BMDAbstract
Stach, 201048RA (n = 58); control (n = 30)Cross-sectionalWrist, MCP2–4Erosions, osteophytes, surface changes, reproducibility, other radiographyFull-length report
Stach, 200949RA (n = 60), control (n = 30)Cross-sectionalMCP2–3BMA, erosions, other radiographyAbstract
  • RA: rheumatoid arthritis; MCP: metacarpophalangeal joints; BMD: bone mineral density; BMA: bone microarchitecture; ERA: early rheumatoid arthritis; JSW: joint space width; PsA: psoriatic arthritis; EHOA: erosive hand osteoarthritis; OA: osteoarthritis; PsO: psoriasis; EIA: early inflammatory arthritis; ACPA: anticitrullinated protein antibodies; PIP: proximal interphalangeal joints; DIP: distal IP joints.