Demographic, laboratory, and clinical characteristics of 186 patients with AAV. Values are n (%) unless otherwise specified.
| Characteristics | Values, n = 186 |
|---|---|
| PR3:MPO-ANCA+, n | 92:78 |
| Diagnosis of GPA, MPA, EGPA, n | 92, 83, 11 |
| Age at diagnosis, yrs, mean (SD) | 64.5 (15.8) |
| Diagnosis delay, mos, median (IQR) | 2 (1–5) |
| Laboratory results | |
| CRP, mg/dl, median (IQR) | 8.7 (2.2–14.8) |
| ESR, mm/h, mean (SD) | 67 (33) |
| Hemoglobin, g/dl, mean (SD) | 11.0 (1.9) |
| Thrombocyte count, × 109/l, mean (SD) | 381 (135) |
| WBC count, × 109/l, median (IQR) | 11 (9–14) |
| Creatinine, mg/dl, median (IQR) | 1.73 (0.84–3.47) |
| Patients with ≥ 3 organ systems involved | 124 (67) |
| Deaths during followup | 66 (36) |
| Endstage renal disease* | 32 (17) |
| Organ systems involved at diagnosis | |
| General | 160 (86) |
| Ear, nose, and throat | 79 (42) |
| Chest | 88 (47) |
| Nervous | 23 (12) |
| Cutaneous | 15 (8) |
| Mucocutaneous and eyes | 11 (6) |
| Cardiovascular | 11 (6) |
| Abdominal | 12 (6) |
| Renal | 134 (72) |
↵* Information on endstage renal disease defined as either commencement of chronic dialysis or renal transplantation at any time during the followup from diagnosis to December 2011. ANCA: antineutrophil cytoplasmic antibody; AAV: ANCA-associated vasculitis; PR3: proteinase 3; MPO: myeloperoxidase; GPA: granulomatosis with polyangiitis; MPA: microscopic polyangiitis; EGPA: eosinophilic GPA; IQR: interquartile range; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; WBC: white blood cell.