Cross-sectional associations between structural abnormalities and grade 2 cartilage defects.
| Study factor | Hip Cartilage Defect, PR (95% CI)* |
|---|---|
| MRI abnormalities | |
| Any hip BML, Y/N | 1.45 (1.15–1.85) |
| Any hip BML, CSA | 1.42 (1.21–1.66) |
| High cartilage signal, Y/N† | 1.20 (0.95–1.52) |
| Hip effusion, Y/N | 0.98 (0.65–1.50) |
| Hip effusion, CSA | 1.14 (1.01–1.30) |
| Radiological abnormalities | |
| Radiological hip OA, Y/N | 1.30 (0.96–1.70) |
| Men | 1.60 (1.13–2.25) |
| Women | 0.80 (0.45–1.40) |
| Interaction, p value | p = 0.04 |
Independent variable: structural abnormalities. Dependent variable: presence of hip cartilage defect.
↵* PR (95% CI) = prevalence ratios (95% CI) adjusted for age, sex, and body mass index and taking into account clustering of observation on subjects at phase 2 and phase 3.
↵† PR (95% CI) further adjusted for presence of hip BML. CSA: cross-sectional area; MRI: magnetic resonance imaging; BML: bone marrow lesions; OA: osteoarthritis.