Characteristics | Values |
---|---|
No. family members | 37 |
Male:female, n | 16:21 |
Sex ratio, n | 1:1.3 |
Ethnicity: white | 37 (100) |
Family members with MWS-associated symptoms | 29 (78) |
Family members with confirmed NLRP3 mutation | 15 (41) |
Male:female, n | 9:6 |
Sex ratio, n | 1:0.7 |
Age at MWS diagnosis, mean (range) | 42 (12–75) |
Symptomatic family members with the A439V mutation | 15/15 (100) |
Family members without confirmed NLRP3 mutation | 22 (59) |
Male:female, n | 7:15 |
Sex ratio, n | 1:2 |
Age at MWS diagnosis, mean (range) | 35 (6–70) |
Symptomatic family members | 14/22 (64) |
FCAS: familial cold autoinflammatory syndrome; MWS: Muckle-Wells syndrome.