Relationship between body weight and improvement in effusion among the study groups. Values are mean ± SD unless otherwise specified.
| Body Weight, kg | Group 1, Spironolactone | Group 2, NSAID | Group 3, Cold Compresses | Group 4, Placebo | Total | p |
|---|---|---|---|---|---|---|
| At baseline | ||||||
| Mean weight, kg | 83.64 ± 10.41 | 83.34 ± 12.85 | 83.24 ± 10.46 | 85.78 ± 10.12 | 84.50 ± 10.98 | 0.589 |
| Pearson correlation with fluid thickness | 0.309, p = 0.029 | 0.342, p = 0.015 | 0.314, p = 0.026 | 0.364, p = 0.009 | 0.335, p < 0.001 | |
| After 2 weeks | ||||||
| No improvement of effusion | 86.14 ± 4.95 | 87.69 ± 11.88 | 83.03 ± 10.68 | 85.86 ± 9.94 | 85.66 ± 10.54 | 0.394 |
| Partial improvement of effusion | 86.40 ± 9.61 | 86.17 ± 10.80 | 82.86 ± 10.68 | 91.80 ± 3.96 | 86.43 ± 9.42 | 0.472 |
| Complete cure of effusion | 82.27 ± 11.39 | 78.67 ± 14.81 | 83.86 ± 10.65 | 74.67 ± 13.32 | 81.56 ± 11.96 | 0.516 |
| p | 0.441 | 0.114 | 0.967 | 0.065 | 0.037 | — |
NSAID: nonsteroidal antiinflammatory drugs.