Table 2.

Association of various immune cells in synovium and IFP with knee pain, assessed by the visual analog scale in 42 patients with endstage knee OA.

VariablesNo. PatientsStandardized β (95% CI)Adjusted Standardized β (95% CI)*
Synovium
  CD4+ T cells220.60 (0.25–1.06)**0.51 (0.09–1.02)**
  CD8+ T cells220.02 (−0.83 to 0.89)0.21 (−0.50 to 1.29)
  Macrophages14−0.34 (−0.68 to 0.19)−0.35 (−0.60 to 0.08)
  Mast cells130.17 (−0.93 to 1.58)−0.25 (−1.71 to 0.74)
IFP
  CD4+ T cells240.19 (−0.41 to 1.05)−0.07 (−0.80 to 0.56)
  CD8+ T cells24−0.21 (−1.01 to 0.35)0.11 (−0.53 to 0.86)
  Macrophages200.36 (−0.10 to 0.86)0.07 (−0.38 to 0.52)
  Mast cells180.20 (−1.21 to 2.77)−0.13 (−1.89 to 1.79)
  • * Adjusted for age and sex.

  • ** P value < 0.05. IFP: infrapatellar fat pad; OA: osteoarthritis.