Univariate associations between joint space variables and clinical features. Values are β (95% CI), with p values.
| Men | Women | All | |
|---|---|---|---|
| Joint space reduction per year of followup | |||
| Age, yrs | −0.001 (−0.008, 0.006) | 0.000 (−0.004, 0.003) | −0.001 (−0.004, 0.002) |
| p | 0.758 | 0.832 | 0.622 |
| BMI at baseline | 0.001 (−0.012, 0.013) | −0.002 (−0.006, 0.003) | −0.001 (−0.006, 0.003) |
| p | 0.909 | 0.492 | 0.619 |
| KL grade | −0.048 (−0.149, 0.053) | −0.042 (−0.095, 0.011) | −0.046 (−0.094, 0.003) |
| p | 0.353 | 0.12 | 0.064 |
| BML | −0.180 (−0.337, −0.022) | −0.072 (−0.163, 0.020) | −0.101 (−0.180, −0.023) |
| p | 0.026 | 0.125 | 0.012 |
| Joint space width at baseline | |||
| Age, yrs | −0.011 (−0.028, 0.006) | −0.010 (−0.021, 0.001) | −0.009 (−0.018, 0.000) |
| p | 0.193 | 0.084 | 0.057 |
| BMI at baseline | −0.003 (−0.034, 0.029) | −0.014 (−0.029, 0.001) | −0.012 (−0.025, 0.001) |
| p | 0.856 | 0.06 | 0.08 |
| KL grade | −0.872 (−1.104, −0.641) | −0.743 (−0.895, −0.592) | −0.780 (−0.907, −0.652) |
| p | <0.001 | <0.001 | <0.001 |
| BML | −0.275 (−0.764, 0.214) | 0.051 (−0.218, 0.321) | −0.020 (−0.261, 0.222) |
| p | 0.263 | 0.706 | 0.871 |
BMI: body mass index; KL: Kellgren-Lawrence; BML: bone marrow lesions.