Table 4.

Associations between joint space variables and clinical features after adjustment for age, sex, and mutual adjustment. Values are β (95% CI), with p values.

Joint Space Reduction, mm per year of followupJoint Space Width, mm at baseline
KL gradea−0.045 (−0.09, 0.00)−0.774 (−0.90, −0.65)**
  p0.068< 0.001
BMLa−0.102 (−0.18, −0.02)*0.003 (−0.24, 0.24)
  p0.0110.983
KL gradeb−0.044 (−0.09, 0.00)−0.782 (−0.91, −0.66)**
  p0.074< 0.001
BMLb−0.103 (−0.18, −0.02)*−0.039 (−0.27, 0.20)
  p0.0110.746
KL gradec−0.043 (−0.09, 0.00)−0.776 (−0.90, −0.65)**
  p0.077< 0.001
BMLc−0.103 (−0.18, −0.02)*−0.015 (−0.25, 0.22)
  p0.0110.901
KL graded−0.077 (−0.16, 0.01)−0.589 (−0.82, −0.36)**
  p0.065< 0.001
BMLd−0.100 (−0.18, −0.02)*0.008 (−0.21, 0.23)
  p0.0130.945

  • ↵a Adjusted for age;

  • ↵b adjusted for sex;

  • ↵c adjusted for age and sex;

  • ↵d adjusted for age, sex, and mutual adjustment (KL grade adjusted for BML and BML adjusted for KL grade);

  • ↵* p < 0.05;

  • ↵** p < 0.01. BML: bone marrow lesions; KL: Kellgren-Lawrence.