Table 1A.

Level of evidence and grading of therapeutic recommendations, according to criteria endorsed by EULAR/EUVAS6,24. From Dougados, et al. Ann Rheum Dis 2004;63:1172–6; with permission.

Method of categorizing level of evidence available for each topic.

Category of EvidenceEvidence Available
1AFrom metaanalysis of randomized controlled trials.
1BFrom at least 1 randomized controlled trial.
2AFrom at least 1 controlled study without randomization.
2BFrom at least 1 quasi-experimental study.
3From descriptive studies, such as comparative studies, correlation studies, or case-control studies.
4From expert committee reports or opinions and/or clinical experience of respected authorities.