Descriptive statistics of study population. Values are n (%) unless otherwise specified.
| Characteristics | First Pregnancy, n = 27 | Second Pregnancy, n = 27 | |
|---|---|---|---|
| Age, yrs, mean (SD) | 31.2 (3.6) | 33.6 (3.4) | |
| Smoking | 3 (11.1) | 2 (7.4) | |
| RA duration, yrs, mean (SD) | 6.5 (5.6) | 8.7 (6.0) | |
| DAS28-CRP first trimester, mean (SD) | 3.84 (1.11) | 3.81 (1.22) | |
| Patients with moderate and high disease activity, DAS28-CRP ≥ 3.2, at first trimester | 19 (70.4) | 17 (63.0) | |
| Prednisone use during pregnancy | 7 (25.9) | 11 (40.7) | |
| SSZ use during pregnancy | 5 (18.5) | 3 (11.1) | |
| Both prednisone and SSZ use during pregnancy | 1 (3.7) | 2 (7.4) | |
| No medication during pregnancy | 14 (51.9) | 11 (40.7) | |
| In Total | |||
| RF-positive | 19 (70.4) | ||
| Anti-CCP–positive | 15 (55.6) | ||
| Erosion | 20 (74.1) | ||
| MTX use ever | 17 (63.0) | ||
RA: rheumatoid arthritis; DAS28: Disease Activity Score in 28 joints; CRP: C-reactive protein; SSZ: sulfasalazine; RF: rheumatoid factor; anti-CCP: anticyclic citrullinated peptide; MTX: methotrexate.