Summary of data from systematic literature review addressing fulfillment of the OMERACT filter by imaging modalities in chronic gout.
XR | CT | US | DECT | MRI | |
---|---|---|---|---|---|
Construct validity* | + | + | + | + | ± |
Content validity† | + | + | + | + | ± |
Criterion validity‡ | + | + | + | + | ± |
Intrareader reliability§ | ± | + | ± | + | ± |
Interreader reliability§ | + | + | + | + | ± |
Discrimination in response to treatment | ± | − | ±¶ | − | − |
Feasibility | + | ? | ? | ? | ? |
↵* Considered present if imaging finding had been confirmed with an alternative imaging modality in at least 1 study.
↵† Considered present if imaging findings measured part of the domain of interest [urate deposition (tophus burden), joint inflammation or structural joint damage].
↵‡ Considered present if abnormality imaged had been directly confirmed with relevant histological assessment or by conformity with strict diagnostic criteria.
↵§ Considered fulfilled if intraclass correlation coefficient > 0.8. +: Data adequate in all domains the imaging modality can address; ±: some data available in all domains or data available only for some domains; −: insufficient or no data; ?: uncertainty because patient acceptability may be important but not yet addressed.
↵¶ For tophus only, not the double contour sign. XR: radiography; CT: computed tomography; DECT: dual-energy computed tomography; MRI: magnetic resonance imaging; US: ultrasound.