PsAMRIS baseline and change scores of the foot.
| PsAMRIS features (range of total score) | Total score | MTP | IP | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Placebo | ABA | Placebo | ABA | Placebo | ABA | |||||||
| Baseline | Change | Baseline | Change | Baseline | Change | Baseline | Change | Baseline | Change | Baseline | Change | |
| Foot | ||||||||||||
| Synovitis (0–18) | 2.6 (1.8 to 3.3) | 0.4 (0.0 to 0.8) | 5.4 (4.8 to 6.1) | −1.2 (−1.3 to −1.1) | 1.6 (0.8 to 2.4) | 0.3 (0.0 to 0.7) | 4.0 (2.7 to 5.1) | −1.1 (−1.1 to 1.0)* | 0.4 (0.2 to 0.8) | 0.1 (0.0 to 0.2) | 0.8 (0.6 to 1.0) | −0.1 (−0.2 to −0.2) |
| Flexor tenosynovitis (0–18) | 0.4 (0.1 to 0.7) | 0.6 (0.3 to 0.8) | 1.0 (0.5 to 1.7) | −0.1 (−0.7 to 0.6) | 0.5 (0.3 to 0.8) | 0.3 (0.1 to 0.5) | 1.0 (0.5 to 1.6) | −0.5 (−0.9 to −0.2) | 0.1 (0.0 to 0.2) | 0.1 (0.0 to 0.2) | 0.1 (0.1 to 0.2) | 0.0 (0.0 to 0.1) |
| Periarticular inflammation (0–12) | 0.1 (0.0 to 0.2) | 0.1 (0.0 to 0.2) | 1.5 (0.3 to 2.1) | −0.3 (−0.4 to −0.1) | 0.1 (0.0 to 0.2) | 0.0 (0.0 to 0.0) | 0.7 (0.2 to 1.7) | −0.1 (−0.4 to 0.0) | 0.0 (0.0 to 0.1) | 0.1 (0.0 to 0.2) | 0.1 (0.0 to 0.1) | −0.1 (−0.1 to 0.0) |
| Bone marrow edema (0–36) | 0.7 (0.3 to 0.9) | 0.0 (0.0 to 0.0) | 2.9 (2.5 to 3.1) | −0.5 (−0.9 to −0.1) | 0.4 (0.3 to 0.6) | 0.0 (0.0 to 0.0) | 1.9 (1.8 to 2.0) | −0.4 (−0.8 to −0.2) | 0.2 (0.0 to 0.4) | 0.0 (0.0 to 0.0) | 1.0 (0.7 to 1.3) | 0.0 (−0.1 to 0.2) |
| Bone erosion (0–120) | 1.3 (0.9 to 1.5) | 0.0 (−0.1 to 0.0) | 3.3 (2.3 to 5.0) | 0.0 (−0.1 to 0.1) | 1.0 (0.9 to 1.2) | 0.0 (−0.1 to 0.0) | 3.0 (1.8 to 4.9) | −0.1 (−0.2 to 0.0) | 0.3 (0.0 to 0.5) | 0.0 (0.0 to 0.0) | 0.4 (0.3 to 0.5) | 0.0 (0.0 to 0.1) |
| Bone proliferation (0–6) | 0.5 (0.2 to 0.8) | 0.0 (−0.1 to 0.0) | 0.2 (0.1 to 0.3) | 0.0 (0.0 to 0.0) | 0.3 (0.2 to 0.5) | 0.0 (−0.1 to 0.0) | 0.1 (0.0 to 0.2) | 0.0 (0.0 to 0.0) | 0.1 (0.0 to 0.2) | 0.0 (0.0 to 0.0) | 0.1 (0.1 to 0.1) | 0.0 (0.0 to 0.0) |
↵* p < 0.05. Scores are presented as the mean (range) of the 3 readers’ mean scores of the 2 readings. PsAMRIS: Psoriatic Arthritis MRI Score; MCP: metacarpophalangeal, PIP: proximal interphalangeal, DIP: distal interphalangeal, MTP: metatarsophalangeal, IP: interphalangeal; ABA: abatacept.