Disease activity at the first HCQ assessment by HCQ level. Values are mean (SD) unless otherwise specified.
| Variables | HCQ < 15 ng/ml, n = 88 | HCQ 15–500 ng/ml, n = 216 | HCQ 500+ ng/ml, n = 382 | p |
|---|---|---|---|---|
| SLEDAI | 2.92 (3.62) | 2.36 (2.89) | 2.20 (2.64) | 0.10* |
| PGA | 0.75 (0.68) | 0.63 (0.63) | 0.60 (0.63) | 0.14 |
| Vitamin D | 37.5 (19.75) | 38.40 (16.87) | 45.52 (15.56) | 0.0021 |
↵* P = 0.04 for trend. HCQ: hydroxychloroquine; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; PGA: physician’s global assessment.