Table 2.

Baseline characteristics for fatigue trajectory groups. Values are mean (SD) or % unless otherwise specified.

Characteristics	Male Participants				Female Participants
Characteristics	Improved, n = 48	n	Moderate-high, n = 54	n	Improved, n = 81	n	Nonimproved^{^‡}, n = 155	n
Age at registration, yrs	62.4 (12.1)	48	58.0 (14.23)	54	59.2 (14.2)	81	51.7 (14.5)^**	155
Employment status
Working now	43.7	48	32.0	53	36.2	80	44.1	152
Retired	52.1		41.5		45.0		24.3
Not working because of illness	0.0		20.7^*		6.2		11.8
Other	4.2		5.8		12.6		19.8
Disease duration, mos, median (IQR)	6.2 (3.0–8.2)	48	6.1 (4.6–11.0)	54	6.3 (4.2–9.2)	81	6.3 (4.4–11.7)	155
1987 RA classification criteria	75.0	48	63.0	54	74.1	81	67.1	155
RF+	62.5	48	53.2	47	54.5	77	56.4	149
DAS28	4.05 (1.31)	38	4.31 (1.47)	40	4.16 (1.08)	63	4.67 (1.15)^**	132
Disability, HAQ	0.93 (0.70)	48	1.52 (0.73) ^**^†	54	1.06 (0.66)	81	1.30 (0.69)^*^†	155
Pain, VAS 0–100	34.5 (22.2)	48	62.3 (24.0) ^**^†	54	40.8 (35.6)	81	53.0 (23.8)^**^†	155
Fatigue, VAS 0–100	43.2 (20.4)	48	65.1 (20.6) ^**^†	54	49.9 (19.6)	81	63.8 (20.8)^**^†	155
Sleep problems, VAS 0–100	33.5 (29.0)	48	51.9 (29.8)^**^†	54	41.2 (27.3)	81	54.3 (29.2)^**^†	155
Stomach problems, VAS 0–100	14.1 (22.9)	48	25.1 (29.9) ^*^†	54	16.0 (25.0)	80	26.5 (27.1)^**^†	153
Steroids	14.6	48	38.9^**	54	17.3	81	23.2	155
β blockers	8.3	48	9.3	54	8.6	81	3.9	155
Thyroxine	4.2	48	1.8	54	8.6	81	11.6	155
Antidepressants	0.0	48	3.7	54	1.2	81	12.9^**	155
DMARD	62.5	48	74.1	54	65.4	81	52.3	155
Analgesics	20.8	48	53.7^**	54	29.6	81	36.8	155
NSAID	41.7	48	38.9	54	32.1	81	49.7^*	155
History of renal disease	0	47	0	54	0	80	1.3	155
History of COPD	10.6	47	22.2	54	21.2	80	29.0	155
History of stroke	0	47	3.7	54	2.5	80	0.6	155
History of depression	14.9	48	20.4	54	16.25	80	44.5^**	155
History of HTN	34.0	48	35.2	54	21.2	80	22.6	155

↵‡ Nonimproved fatigue, Moderate-high, and High fatigue participants.
↵* p < 0.05.
↵** p < 0.01.
↵† Clinically significant. IQR: interquartile range; RA: rheumatoid arthritis; RF: rheumatoid factor; DAS28: Disease Activity Score at 28 joints; HAQ: Health Assessment Questionnaire; VAS: visual analog scale; DMARD: disease-modifying antirheumatic drugs; NSAID: nonsteroidal antiinflammatory drugs; COPD: chronic obstructive pulmonary disease; HTN: hypertension.