Characteristics of the participants. Participants were grouped by the median of the IPFP volume (19.1 cm3), and results were shown as mean (95% CI) or frequency (%).
| Low IPFP volume, n = 88 | High IPFP volume, n = 86 | p* | |
|---|---|---|---|
| Age, yrs | 54.35 (52.64–56.06) | 56.31 (54.50–58.13) | 0.104 |
| Males/females | 1 (1.1)/87 (98.9) | 24 (27.9)/62 (72.1) | < 0.001 |
| Height, cm | 155.21 (154.26–156.16) | 163.15 (161.59–164.70) | < 0.001 |
| Weight, kg | 60.39 (58.57–62.20) | 69.31 (66.95–71.68) | < 0.001 |
| BMI (kg/m2) | 25.12 (24.26–25.97) | 26.04 (25.20–26.89) | 0.114 |
| MT cartilage volume | 1.10 (1.06–1.14) | 1.34 (1.26–1.41) | < 0.001 |
| LT cartilage volume | 1.04 (1.00–1.09) | 1.26 (1.18–1.34) | < 0.001 |
| Patellar cartilage volume | 1.61 (1.52–1.70) | 2.26 (2.12–2.39) | < 0.001 |
| Knee ROA | 79 (89.8) | 76 (88.3) | 0.931 |
| KL grade 1 | 9 (10.2) | 10 (11.6) | 0.326 |
| KL grade 2 | 40 (45.5) | 38 (44.2) | 0.370 |
| KL grade 3 | 34 (38.6) | 28 (32.6) | 0.769 |
| KL grade 4 | 5 (5.7) | 10 (11.6) | 0.465 |
| MTF cartilage defect | 87 (98.9) | 81 (94.2) | 0.427 |
| LTF cartilage defect | 87 (98.9) | 84 (97.6) | 0.299 |
| Patellar cartilage defect | 75 (85.2) | 68 (79.1) | 0.066 |
| MTF BML | 32 (36.4) | 26 (30.2) | 0.477 |
| LTF BML | 29 (33.0) | 26 (30.2) | 0.987 |
| Patellar BML | 49 (55.6) | 42 (48.8) | 0.586 |
↵* t test, or chi-square test. IPFP: infrapatellar fat pad; BMI: body mass index; ROA: radiographic osteoarthritis; MT: medial tibial; LT: lateral tibial; MTF: medial tibiofemoral; LTF: lateral tibiofemoral; KL: Kellgren-Lawrence arthritis grading scale; BML: bone marrow lesions.