Predictors of relapse. Adjusted for baseline characteristics (i.e., age, sex, lung involvement, and serum creatinine level) and followup data (i.e., ANCA level and immunosuppressive therapy including PSL, per 1.0 mg/day, and use of immunosuppressive agents).
| Predictors | Multivariate Model | |
|---|---|---|
| HR (95% CI) | p* | |
| Age, per yr | 0.99 (0.96–1.03) | 0.562 |
| Female vs male | 1.46 (0.72–2.96) | 0.290 |
| Lung involvement | 2.29 (1.13–4.65) | 0.022 |
| Serum creatinine, per 1.0 mg/dl | 1.10 (0.94–1.29) | 0.218 |
| ANCA level increase | 17.4 (8.42–36.0) | < 0.001 |
| Immunosuppressive treatment | ||
| PSL, per 1.0 mg/day | 1.04 (0.97–1.11) | 0.274 |
| Use of immunosuppressive agent | 1.24 (0.55–2.80) | 0.611 |
↵* Cox regression analysis. ANCA: antineutrophil cytoplasmic antibody; PSL: prednisolone.