Table 2.

Characteristics and distribution of clinical manifestations in the Italian cohort of patients with APS included in the study. Values are n (%) unless otherwise specified.

Patient Characteristics or Clinical ManifestationsPAPSSAPS
Patients, n1525
Age, yrs, median (range)32 (20–62)35 (12–76)
Women14 (93)24 (96)
Fetal losses3 (20)5 (20)
Anti-CL IgG10 (67)15 (60)
Anti-CL IgM9 (60)16 (64)
Anti-β2-GP1 IgG7 (88)10 (40)
Anti-β2-GP1 IgM7 (50)9 (36)
ANA8 (53)25 (100)
LA10 (71)17 (68)
Thrombosis venous8 (53)17 (68)
Thrombosis arterial7 (47)6 (24)
C3 low level0 (0)11 (44)
  • APS: antiphospholipid syndrome; PAPS: primary APS; SAPS: secondary APS; CL: cardiolipin; Ig: immunoglobulin; β2-GP1: β2 glycoprotein 1; ANA: antinuclear antibodies; LA: lupus anticoagulant; C3: complement factor 3.