Cohort Patient classification | Serbian | Italian | ||
---|---|---|---|---|
PAPS | SAPS | PAPS | SAPS | |
a-FHpos/a-FHneg, n | 10/63 | 10/23 | 5/10 | 9/16 |
Manifestation | n (% a-FHpos/% a-FHneg) | n (% a-FHpos/% a-FHneg) | ||
Obstetric disorder | 59 (90/79) | 21 (50/70) | 3 (20/20) | 5 (22/19) |
Coagulation disorder | 41 (44/60) | 22 (70/65) | ||
Hematological disorder | — | — | 6 (40/40) | 16 (67/63) |
Heart disorder | 13 (40/14)* | 17 (50/55) | ||
Neurological disorder | 33 (40/46) | 25 (60/83) | 4 (40/20) | 7 (33/25) |
Pulmonary disorder | 9 (10/13) | 3 (20/4) | — | — |
Renal disorder | 3 (0/5) | 0 (—/—) | 1 (20/0) | 9 (56/25) |
Cutaneous disorder | 17 (30/23) | 30 (70/100)* | 1 (0/10) | 18 (100/56)* |
Arthritis | 5 (10/6) | 25 (50/87)* | 0 (—/—) | 14 (44/63) |
↵Significant difference in ratio between manifestation-positive patients in the 2 antibody groups was calculated using Pearson chi-square test and indicated as * p < 0.05. FH: complement factor H; APS: antiphospholipid syndrome; PAPS: primary APS; SAPS: secondary APS; a-FHpos: FH autoantibody–positive; a-FHneg: FH autoantibody–negative.