Table 3.

Correlation coefficients of 14-3-3η protein and antibodies with clinical and serological measures in patients with early RA. Correlation between age and HAQ was established with a Pearson product-moment correlation as both variables were normally distributed according to Shapiro-Wilk normality testing; all other correlations are Spearman rank correlation.

Variable	Age, Yrs	Disease Duration	DAS28	HAQ	ESR	CRP	RF	ACPA	14-3-3η
n	114	114	114	52	114	113	114	113	114
14-3-3η	−0.05	0.04	0.06	0.24	0.19^*	0.12	0.65^†	0.54^†	—
14-3-3η AAb	0.00	0.02	0.18	−0.05	0.27^**	0.13	0.06	−0.10	−0.02

↵* p ≤ 0.05.
↵** p < 0.01.
↵† p < 0.0001. RA: rheumatoid arthritis; HAQ: Health Assessment Questionnaire; DAS28: Disease Activity Score at 28 joints; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; RF: rheumatoid factor; ACPA: anticitrullinated protein antibodies; AAb: autoantibody.