Clinical characteristics of severe and very severe PSD groups in RA subjects who satisfy modified ACR research criteria for FM. Groups differ for all symptoms at p < 0.5. ACR+ and ACR± groups were analyzed separately. Values are mean (SD) or % unless otherwise specified.
| Variables | PSD, 12–19, ACR+ | PSD, 20–31, ACR+ | PSD, 12–19, ACR± | PSD, 20–31, ACR± |
|---|---|---|---|---|
| PSD category | Severe | Very severe | Severe | Very severe |
| Subjects, n | 288 | 209 | 494 | 233 |
| Patients | 10.5 | 7.7 | 18.1 | 8.5 |
| Age, yrs | 62.3 (12.5) | 57.8 (13.2) | 64.0 (12.4) | 54.4 (13.1) |
| Male, % | 14.9 | 11.5 | 15.4 | 12.0 |
| Pain, 0–10 | 5.3 (2.4) | 6.8 (2.0) | 5.2 (2.4) | 6.5 (2.2) |
| Global severity, 0–10 | 5.2 (2.0) | 6.3 (1.8) | 4.8 (2.1) | 6.0 (2.0) |
| HAQ, 0–3 | 1.4 (0.6) | 1.7 (0.5) | 1.4 (0.6) | 1.6 (0.5) |
| SF-36, PCS | 30.8 (8.2) | 27.5 (7.0) | 31.3 (8.6) | 28.3 (7.6) |
| SF-36, MCS | 41.2 (11.1) | 38.2 (11.4) | 43.4 (11.5) | 39.7 (12.2) |
| GAD anxiety score | 1.6 (1.6) | 2.0 (1.9) | 1.4 (1.6) | 1.9 (1.9) |
| GAD probable anxiety disorder | 22.3 | 30.6 | 18.0 | 27.5 |
| PHQ-2 depression score | 1.8 (1.7) | 2.2 (1.9) | 1.6 (1.6) | 2.0 (1.9) |
| PHQ-2 probable depression disorder | 26.1 | 34.8 | 21.6 | 31.2 |
| PHQ-4 score | 3.4 (2.9) | 4.3 (3.6) | 2.9 (2.9) | 3.9 (3.6) |
| SSS-8 score | 14.3 (4.8) | 17.5 (5.0) | 13.1 (5.0) | 16.6 (5.7) |
| SSS-8 categories | ||||
| None to minimal, 0–3 | 1.1 | 0.0 | 1.7 | 1.3 |
| Low, 4–7 | 5.3 | 0.5 | 10.3 | 4.3 |
| Medium, 8–11 | 23 | 9.1 | 29.1 | 11.6 |
| High, 12–15 | 33.9 | 31.6 | 29.1 | 29.2 |
| Very high, 16–32 | 36.7 | 58.9 | 29.8 | 53.6 |
| WPI, 0–19 | 8.2 (2.3) | 16.3 (2.8) | 8.6 (3.0) | 16.5 (2.8) |
| SSS, 0–12 | 7.2 (1.8) | 8.2 (2.0) | 6.2 (2.2) | 7.7 (2.4) |
| FM research survey criteria | 100.0 | 100.0 | 58.3 | 89.7 |
| PSD, 0–31 | 15.4 (2.1) | 24.5 (3.0) | 14.8 (2.3) | 24.2 (3.0) |
| Widespread pain | 87.8 | 100.0 | 86.4 | 100.0 |
PSD: polysymptomatic distress scale; RA: rheumatoid arthritis; ACR: American College of Rheumatology; FM: fibromyalgia; HAQ: Health Assessment Questionnaire-Disability Index; SF-36: Medical Outcomes Study Short Form-36; PCS: physical component summary score; MCS: mental component summary score; GAD: generalized anxiety disorder; PHQ-2: patient health questionnaire-2; PHQ-4: patient health questionnaire-4; SSS-8: somatic symptom score; WPI: widespread pain index; SSS: symptom severity scale.