Demographic and baseline clinical data. Values are mean ± SD unless otherwise specified.
| Clinical Data | LN Group | HTN Group | Healthy Controls | p* |
|---|---|---|---|---|
| No. patients | 73 | 13 | 25 | — |
| Female:male | 71:2 | 8:5 | 18:7 | p < 0.0001 |
| Age, yrs | 41.3 ± 9.8 | 57.2 ± 17.0 | 36.4 ± 4.3 | p < 0.0001 |
| Serum creatinine, µmol/l | 106.7 ± 121.4 | 102.9 ± 54.7 | 79.8 ± 16.9 | p = 0.5 |
| Estimated GFR, ml/min | 94.0 ± 49.8 | 72.7 ± 30.1 | 97.6 ± 22.9 | p = 0.2 |
| Proteinuria, g/day | 2.8 ± 1.5 | 2.2 ± 3.9 | 0.0 ± 0.0 | p < 0.0001 |
↵* Difference between the LN and HTN groups (by Student t test). LN: lupus nephritis; HTN: hypertensive nephrosclerosis; GFR: glomerular filtration rate.