Table 4.

Reproducibility of IRT and LSCI for each ROI at baseline and following cold challenge for both primary RP and SSc. Values are ICC (95% CI). N = 41, unless stated otherwise.

ROICameraBt0t5t10t15
1IRT*0.51 (0.24–0.71)0.61 (0.36–0.78)0.52 (0.25–0.72)0.5 (0.23–0.7)0.54 (0.28–0.73)
LSCI0.62 (0.39–0.78)0.86 (0.75–0.92)0.52 (0.25–0.71)0.34 (0.04–0.58)0.47 (0.19–0.68)
2IRT*0.51 (0.24–0.71)0.56 (0.3–0.75)0.54 (0.28–0.73)0.54 (0.28–0.73)0.55 (0.28–0.73)
LSCI0.63 (0.4–0.78)0.59 (0.33–0.76)0.65 (0.43–0.79)0.54 (0.28–0.73)0.30 (0–0.55)
3IRT**0.59 (0.33–0.76)0.6 (0.35–0.77)0.55 (0.28–0.73)0.63 (0.4–0.79)0.70 (0.5–0.83)
LSCI*0.55 (0.29–0.73)0.79 (0.63–0.89)0.5 (0.22–0.7)0.42 (0.13–0.65)0.55 (0.29–0.73)
  • * n = 40.

  • ** n = 39. IRT: infrared thermography; LSCI: laser speckle contrast imaging; ROI: region of interest; RP: Raynaud phenomenon; SSc: systemic sclerosis; B: baseline assessment at 23°C; t0: assessments immediately following cold challenge; t5: perfusion 5 min post cold challenge; t10: perfusion 10 min post cold challenge; t15: perfusion 15 min post cold challenge.