CV in studies of calprotectin concentrations. Levels reported as median (range); the median used as an estimator (∼) of the mean and the SD estimated by the range/422. In levels presented as median and interquartile ranges, the CV could not be derived23, denoted as NA.
| Study | n | Calprotectin, µg/l | CV, % |
|---|---|---|---|
| Plasma calprotectin | |||
| Berntzen, et al24 | 47 | 2602 (1831) | 70 |
| Berntzen, et al25 | 41 | 9400 (985–46,078) | ∼120 |
| Brun, et al26 | 43 | 12,185 (540–49,486) | ∼100 |
| Brun, et al27 | 70 | 8406 (6088) | 72 |
| Madland, et al29 | 56 | NA | NA |
| Drynda, et al30 | 23 | 14,516 (12,949) | 89 |
| 37 | 15,516 (11,566) | 75 | |
| Hammer, et al33 | 145 | 1800 (300–8700) | ∼117 |
| De Seny, et al34 | 34 | 607 (145–3387) | ∼133 |
| Hammer, et al35 | 61 | 1923 (1511) | 79 |
| Hammer, et al36 | 124 | NA | NA |
| Hammer, et al38 | 20 | 2020 (560–20,440) | ∼240 |
| Serum calprotectin | |||
| De Rycke, et al31 | 40 | 1075 (210–11,390) | ∼260 |
| Sunahori, et al32 | 17 | 38,900 (6000) | 15 |
| Andrés Cerezo, et al37 | 43 | 5990 (880) | 15 |
| García-Arias, et al39 | 60 | 4700 (3600) | 77 |
| 20 | 6475 (3519) | 54 | |
| Choi, et al40 | 170 | NA | NA |
| Synovial calprotectin | |||
| Berntzen, et al25 | 41 | 18,156 (1951–375,368) | ∼492 |
| Burmeister, et al28 | 11 | 1,739,081 (2,640,000) | 152 |
| Drynda, et al30 | 23 | 475,000 (280,077) | 59 |
| De Rycke, et al31 | 20 | 25,838 (234–234,431) | ∼906 |
| Sunahori, et al32 | 17 | 54,800 (7200) | 13 |
CV: coefficient of variation; NA: not applicable.