Manifestations | Patients with Manifestations | Patients without Manifestations | p | ||
---|---|---|---|---|---|
No. Patients | MASP-1 | No. Patients | MASP-1 | ||
SDI-positive vs -negative | 43 | 10,512 (5554–29,684) MASP-3 | 15 | 8060 (6225–16,590) MASP-3 | 0.0195 |
Nephritis | 7 | 3920 (3394–4952) MASP-2 | 51 | 5096 (2856–9910) MASP-2 | 0.0409 |
Anemia | 9 | 176 (69–419) MAp19 | 49 | 272 (55–772) MAp19 | 0.0194 |
Low C3 count | 25 | 182 (74–442) | 33 | 129 (22–290) | 0.0015 |
Anti-dsDNA–positive vs -negative | 34 | 171.5 (22–442) | 24 | 122 (30–295) | 0.026 |
Positive SDI score is a score > 0. Anemia = plasma hemoglobin < 7.3 mmol/l. Measurement of anti-dsDNA was considered positive > 10 × 103 IU/l. MASP: mannan-binding lectin-associated serine proteases; MAp: mannan-binding lectin-associated protein; SLE: systemic lupus erythematosus; SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; C3: complement factor 3; MAp19: MBL-associated protein of 19 kDa.