Table 3.

Differences in plasma levels of MASP and MAp in patients with and without characteristic manifestations of SLE. Values are median (range) unless otherwise specified.

ManifestationsPatients with ManifestationsPatients without Manifestationsp
No. PatientsMASP-1No. PatientsMASP-1
SDI-positive vs -negative4310,512 (5554–29,684)
MASP-3
158060 (6225–16,590)
MASP-3
0.0195
Nephritis73920 (3394–4952)
MASP-2
515096 (2856–9910)
MASP-2
0.0409
Anemia9176 (69–419)
MAp19
49272 (55–772)
MAp19
0.0194
Low C3 count25182 (74–442)33129 (22–290)0.0015
Anti-dsDNA–positive vs -negative34171.5 (22–442)24122 (30–295)0.026
  • Positive SDI score is a score > 0. Anemia = plasma hemoglobin < 7.3 mmol/l. Measurement of anti-dsDNA was considered positive > 10 × 103 IU/l. MASP: mannan-binding lectin-associated serine proteases; MAp: mannan-binding lectin-associated protein; SLE: systemic lupus erythematosus; SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; C3: complement factor 3; MAp19: MBL-associated protein of 19 kDa.