Table 3.

Relationship between BMI and better response to TCZ at 6 months.

BMI	n (%)	p	OR (95% CI)	p	AOR (95% CI)	p
Global EULAR Response
< 25 kg/m²	84 (80)	0.21	1		1
25–30 kg/m²	30 (70)		0.57 (0.25–1.29)	0.18	0.45 (0.16–1.24)	0.13
> 30 kg/m²	25 (86)		1.56 (0.49–4.97)	0.45	1.19 (0.31–4.48)	0.78
> 25 kg/m²	55 (76)	0.56	0.80 (0.39–1.66)	0.56	0.64 (0.26–1.60)	0.34
Remission
< 25 kg/m²	48 (46)	0.13	1		1
25–30 kg/m²	12 (28)		0.46 (0.21–0.99)	0.04	0.41 (0.14–1.16)	0.09
> 30 kg/m²	12 (41)		0.83 (0.36–1.92)	0.67	0.61 (0.21–1.70)	0.34
> 25 kg/m²	24 (33)	0.09	0.59 (0.31–1.10)	0.10	0.50 (0.22–1.14)	0.09
Low Disease Activity
< 25 kg/m²	66 (63)	0.17	1		1
25–30 kg/m²	22 (51)		0.61 (0.30–1.26)	0.18	0.59 (0.23–1.55)	0.28
> 30 kg/m²	21 (72)		1.55 (0.62–3.83)	0.34	1.41 (0.46–4.36)	0.54
> 25 kg/m²	43 (60)	0.67	0.87 (0.47–1.62)	0.67	0.84 (0.37–1.91)	0.68

AOR: OR adjusted for age, sex, square root of disease duration, presence of erosive lesions; rheumatoid factor, anticitrullinated peptide antibodies, erosive status, concomitant treatment with DMARD (methotrexate, leflunomide, sulfasalazine, hydroxychloroquine, or azathioprine); baseline DAS28; logarithm of baseline CRP; and square root of baseline ESR. BMI: body mass index; TCZ: tocilizumab; EULAR: European League Against Rheumatism; DMARD: disease-modifying antirheumatic drug; DAS28: Disease Activity Score in 28 joints; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate.