Table 2.

Frequency of HLA-DRB1 shared epitope (SE) alleles in the total number of patients (291) with mild and severe rheumatoid arthritis (RA).

Patients with Mild RA, n = 146Patients with Severe RA, n = 145p
Allele Frequency
SE Alleles
  DRB1*01010.0820.0590.275
  DRB1*01020.0620.041
  DRB1*04010.0410.045
  DRB1*04040.0510.048
  DRB1*04050.0510.079
  DRB1*04080.010.031
  DRB1*04100.010
  DRB1*10010.0340.024
  DRB1*14020.0170.024
Frequency of patients carrying SE alleles
  Any SE58.9%60.7%0.756
  Single SE45.9%51.0%0.555
  Double SE13.0%9.7%