Hemodynamic variables of PH associated with patients with PA and patients with IPAH. Values are mean ± SD or n (%) unless otherwise specified.
| Characteristics | PH Due to PA, n = 12 | IPAH, n = 30 | p† |
|---|---|---|---|
| Female sex, n | 11 | 20 | NS |
| mPAP, mmHg | 51.6 ± 11.3 | 53.0 ± 18.0 | NS |
| mRAP, mmHg | 6.6 ± 2.6 | 5.6 ± 3.1 | NS |
| Qp/Qs ratio | 0.8 ± 0.3 | 1.0 ± 0.3 | 0.02 |
| PVR, dyne/s/cm5 | 1157.1 ± 442.9 | 1204.0 ± 538.0 | NS |
| CI, l/min/m2 | 2.0 ± 0.5 | 3.0 ± 1.2 | 0.05 |
| VO2 max, ml/kg/min | 11.5 ± 1.7 | 13.4 ± 2.8 | 0.04 |
| SvO2, % | 57.7 ± 3.9 | 68.5 ± 8.6 | 0.01 |
| Inhaled iloprost | |||
| Elevated CI | 12 (100) | 12 (40.0) | 0.001 |
| Decreased PVR > 20% | 12 (100) | 10 (33.3) | < 0.001 |
| Decreased mPAP > 20% | 12 (100) | 10 (33.3) | < 0.001 |
| Decreased percentage of PVR, % | 27.1 ± 4.4 | 16.6 ± 5.8 | < 0.001 |
| Decreased percentage of mPAP, % | 28.7 ± 2.3 | 15.6 ± 6.6 | 0.002 |
| Acute vasodilator responders | 12 (100) | 10 (33.3) | < 0.001 |
↵† Only statistically significant p values are shown. PH: pulmonary hypertension; PA: pulmonary arteritis; IPAH: idiopathic pulmonary arterial hypertension; mPAP: mean pulmonary artery pressure; mRAP: mean right atrial pressure; Qp/Qs ratio: pulmonary to systemic flow; VO2 max: average peak oxygen uptake; SvO2: mixed venous oxygen saturation; PVR: pulmonary vascular resistance; NS: nonsignificant; CI: cardiac index.