Table 3.

Association between patterns of cumulative joint damage (CJD) and the presence of DRB1 shared epitope (SE) alleles in patients with rheumatoid arthritis.

Hand/foot Imbalance, n = 138pFinger/wrist Imbalance, n = 145pErosion/space-narrowing Imbalance, n = 140p
HLA-DRB1Hands, n = 68, n (%)Feet, n = 70, n (%)Fingers, n = 72, n (%)Wrists, n = 73, n (%)Erosion, n = 70, n (%)Space narrowing, n = 70, n (%)
SE
   Positive43 (46.2)50 (53.8)0.30549 (51.0)47 (49.0)0.64052 (57.1)39 (42.9)0.021
   Negative25 (55.6)20 (44.4)23 (46.9)26 (53.1)18 (36.7)31 (63.3)
SE dose
   Single37 (47.4)41 (52.6)0.59740 (50.0)40 (50.0)0.64842 (56.8)32 (43.2)0.877
   Double6 (40.0)9 (60.0)9 (56.3)7 (46.8)10 (58.8)7 (41.2)
  • Significant p value is given in bold face. Hand-dominant (h/f score > 3.74); foot-dominant (h/f score < 1.69); finger-dominant (f/w score > 1.92); wrist-dominant (f/w score < 0.93); erosion-dominant (e/sn score > 2.38); space narrowing–dominant (e/sn score < 1.58).