Results of the ESSDAI respiratory domain and symptoms evaluated by the ESSPRI, and the SGRQ and radiographic findings of computed tomography of the chest in all the 51 patients with pSS, as well as patients with pSS with (+) and without (−) COPD. Radiographical signs of ILD represent traction bronchiectasis, ground glass attenuation, or honeycombing. Values are mean ± SD or % with abnormal findings unless otherwise specified.
| Signs and symptoms | All Patients with pSS, n = 51 | pSS + COPD, n = 21 | pSS – COPD, n = 30 | p, pSS + vs–COPD |
|---|---|---|---|---|
| ESSDAI respiratory domain score > 0 | 55 | 52 | 57 | 0.762 |
| Low activity | 39 | 38 | 40 | 0.891 |
| Moderate activity | 14 | 10 | 17 | 0.685 |
| High activity | 2 | 5 | 0 | 0.412 |
| ESSPRI total score | 6 ± 2 | 6 ± 3 | 6 ± 2 | 0.281 |
| SGRQ total score | 21 ± 16 | 24 ± 17 | 19 ± 16 | 0.232 |
| SGRQ symptom score | 27 ± 22 | 31 ± 20 | 24 ± 22 | 0.185 |
| SGRQ activity score | 33 ± 24 | 36 ± 27 | 31 ± 23 | 0.527 |
| SGRQ impact score | 13 ± 14 | 15 ± 15 | 11 ± 13 | 0.403 |
| Radiographic findings | ||||
| Radiographic abnormalities | 65 | 81 | 53 | 0.073 |
| Air trapping | 35 | 38 | 33 | 0.726 |
| Reticular pattern | 33 | 52 | 20 | 0.016 |
| Central bronchiectasis | 26 | 43 | 13 | 0.024 |
| Traction bronchiectasis | 8 | 5 | 10 | 0.634 |
| Cysts | 29 | 24 | 33 | 0.463 |
| Emphysema | 14 | 29 | 3 | 0.015 |
| Ground glass attenuation | 12 | 5 | 17 | 0.381 |
| Honeycombing | 0 | 0 | 0 | NA |
| ILD signs | 17 | 10 | 23 | 0.277 |
ESSDAI: EULAR Sjögren Disease Activity Index; ESSPRI: EULAR Sjögren Patient Reported Index; SGRQ: St. George’s Respiratory Questionnaire; pSS: primary Sjögren syndrome; COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; NA: not assessed; EULAR: European League Against Rheumatism.