Two-dimensional echocardiographic variables in the study population. Comparison between patients with SLE and control subjects. Values are mean ± SD unless otherwise specified.
| Characteristics | SDI = 0, n = 58 | SDI ≥ 1, n = 44 | Controls, n = 32 |
|---|---|---|---|
| LA dimension, mm | 35.2 ± 4.3 | 34.7 ± 3.9 | 33.3 ± 4.1 |
| LV end-diastolic dimension, mm | 46.3 ± 4.1 | 47.6 ± 4.5 | 45.9 ± 3.5 |
| LV end-systolic dimension, mm | 29.2 ± 2.1 | 29.4 ± 2.4 | 28.5 ± 2.1 |
| Septal thickness, mm | 8.4 ± 0.7 | 8.5 ± 0.7 | 8.2 ± 0.8 |
| Posterior wall thickness, mm | 8.3 ± 0.7 | 8.4 ± 0.7 | 8.0 ± 0.8 |
| Left ventricular mass, g | 125.4 ± 24.0 | 133.6 ± 23.3*† | 119.2 ± 20.8 |
| Left ventricular mass index, g/m2 | 73.0 ± 20.9 | 77.6 ± 18.5* | 68.8 ± 15.9 |
| LV emptying fraction, % | 65.1 ± 4.7 | 67.0 ± 6.5 | 66.5 ± 5.9 |
| E, m/s | 0.79 ± 0.31 | 1.02 ± 0.33*† | 0.70 ± 0.18 |
| A, m/s | 0.65 ± 0.33 | 0.48 ± 0.16*† | 0.56 ± 0.18 |
| E/A ratio | 1.28 ± 0.12 | 2.23 ± 0.17*† | 1.30 ± 0.23 |
| E′, cm/s | 9.0 ± 1.4 | 8.3 ± 1.4 | 9.2 ± 2.3 |
| E/ E′ ratio | 8.5 ± 3.5 | 13.0 ± 3.4*† | 7.6 ± 0.3 |
| Frequency of E/ E′ ratio > 8, n (%) | 15 (25.8)* | 32 (72.7)*† | 2 (6) |
| Frequency of E/ E′ ratio > 15, n (%) | 7 (12.0)* | 12 (27.2)* | 0 (0) |
| Deceleration time, ms | 171.2 ± 24.2 | 178.2 ± 32.3 | 169.1 ± 30.5 |
↵* p < 0.05, comparison between SLE and control subjects.
↵† p < 0.05, comparison between the 2 SLE groups. SDI: Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; LA: left atrial; LV: left ventricular; E: mitral early diastolic velocity; A: mitral late diastolic velocity; E′: early diastolic mitral annular velocity; SLE: systemic lupus erythematosus.