Table 1.

Baseline comparison of cases of incident cardiovascular (CV) events and controls sampled from a cohort of patients with early rheumatoid arthritis.

VariableCases, n = 279Controls, n = 3348
Matching variables
  Patient age, yrs, mean ± SD64 ± 1264 ± 12
  Mean followup time, days, mean ± SD238 ± 196238 ± 196
CV risk factors
  Diabetes mellitus8229.456416.8
Other comorbid conditions
  Any malignancy227.92878.6
Concurrent drug use
  Pain relievers
  CV medications
    ACE inhibitors531957317.1
    β blockers6824.454116.2
    Lipid-lowering agents8530.585825.6
    Calcium channel blockers6121.949414.8
    Other CV drugs7426.556016.7
  • Concurrent drug use was defined as any use in the period of 90 days prior to the event date;

  • Other CV drugs include cardiac glycosides, antiarrhythmic agents, hypotensive agents, vasodilating agents, and phosphodiesterase inhibitor. COXIB: cyclooxygenase inhibitors; NSAID: nonsteroidal antiinflammatory drugs; ACE: angiotensin-converting enzyme; COPD: chronic obstructive pulmonary disease.