Enthesitis measures used in randomized controlled trials in psoriatic arthritis.
| Enthesis Measure | Method (score range) | Trials in PsA | Validation in PsA |
|---|---|---|---|
| Modified Mander Enthesitis Index25,25a | Tenderness at 21 sites, scored at each site on 4-point scale: 0 = no pain; 1 = mild tenderness; 2 = moderate tenderness; 3 = wince or withdrawal. 1st cervical spinous process; 2nd cervical spinous process; 7th cervical spinous process; 1st thoracic spinous process; 12th thoracic spinous process; 1st lumbar spinous process; 5th lumbar spinous process; 1st sacral spinal process; symphysis pubis; greater trochanters, left, right (L,R); pelvic abductor origin (L,R); anterior superior border of the iliac crest (L,R); ischial tuberosity (L,R); Achilles tendon insertion (L,R); plantar fascia insertion (L,R) | Clegg 199615 | No |
| IMPACT Index9 | Tenderness (yes/no) at 4 sites (0–4); Achilles tendon insertion (L,R); Plantar fascia insertion (L,R) | Antoni 20058,9; Mease 200510; Genovese 200711; Gottlieb 200913; Sterry 201014 | No |
| Maastricht AS Enthesitis Score (MASES)26 | Tenderness (yes/no) at 13 sites (0–13). 1st Costochondral joint (L,R); 7th Costochondral joint (L,R); Posterior superior iliac spine (L,R); Anterior superior iliac spine (L,R); Iliac crest (L,R); 5th Lumbar spinous process; Proximal insertion of Achilles tendon (L,R) | Kavanaugh 201418 Ritchlin 201419 | No |
| PsA Modified MASES12 | Tenderness (yes/no) at 15 sites (0–15). 1st Costochondral joint (L,R); 7th Costochondral joint (L,R); Posterior superior iliac spine (L,R); Anterior superior iliac spine (L,R); Iliac crest (L,R); 5th Lumbar spinous process; Proximal insertion of Achilles tendon (L,R); Plantar fascia insertion (L,R) | Kavanaugh 20097,12; McInnes 201316 | No |
| Leeds Enthesitis Index (LEI)5 | Tenderness (yes/no) at 6 sites (0–6); lateral epicondyle (L,R); medial femoral condyle (L,R); Achilles tendon insertion (L,R) | Mease 201417 | Yes27, clinical LEI, odds ratio: 2.16 (0.81–5.70) for PsA vs RA |