Table 4.

Association of abnormal audiovestibular symptoms with demographic and clinical variables in 60 patients with psoriatic arthritis (PsA).

VariablesOR (95% CI)p
Age, yrs, at the time of study, by yr1.05 (1.00–1.11)0.07
Age, yrs, at the time of disease diagnosis, by yr1.02 (0.98–1.05)0.37
Disease duration, mo1.00 (0.99–1.01)0.77
Patterns of PsA
  Polyarticular1.51 (0.53–4.24)0.43
  Oligoarticular0.57 (0.20–1.62)0.29
  MutilansN/A
  Distal interphalangeal joints only0.71 (0.04–11.8)0.81
  Spondylitis0.69 (0.13–3.73)0.66
Presence of classic cardiovascular risk factors*0.51 (0.17–1.50)0.22
CRP (mg/l) at disease diagnosis1.02 (0.98–1.06)0.36
ESR (mm/first h) at disease diagnosis1.02 (0.99–1.06)0.13
CRP (mg/l) at the time of the study1.11 (1.00–1.23)0.06
ESR (mm/first h) at the time of the study1.06 (1.00–1.12)0.05
Patients treated with MTX alone0.42 (0.06–2.77)0.37
Initially treated with MTX and then with other DMARD+0.95 (0.15–6.06)0.96
Patients treated with anti-TNF-α therapy#2.41 (0.67–8.70)0.18
  • * One or more of the following: hypertension, dyslipidemia, diabetes, obesity, and smoking history.

  • + Conventional DMARD (generally leflunomide and less commonly sulfasalazine) or biologic DMARD–anti-TNF-α therapy (adalimumab, infliximab, or etanercept) alone or in combination with MTX.

  • # In most cases in combination with MTX. CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; MTX: methotrexate; DMARD: disease-modifying antirheumatic drug; TNF-α: tumor necrosis factor-α; N/A: not available.