Table 1.

Characteristics of participants at baseline, n = 430.

CharacteristicsMean (SD, range), or %
Age, yrs63.0 (7.2, 51–79)
Male sex, %49
BMI, kg/m227.6 (4.4, 19–46)
ROA present, %57
Knee pain present, %49
MRI measures
  Tibiofemoral cartilage volume, mm313,417 (3267, 7167–25,401)
  Cartilage defects present†, %32
  BML present, %43
    Mean BML size, tibiofemoral, mm2101 (115, 5–727)
    Mean ordinal score, tibiofemoralϕ2.3 (1.6, 1–10)
  Total meniscal pathology score‡5.6 (1.3, 0–10)
  Total tibial bone area, mm23384 (472, 2405–4696)

  • ↵† Defined as grade 2 or higher.

  • ↵ϕ Possible range 0–12.

  • ↵‡ Possible range 0–18. BMI: body mass index; ROA: radiographic osteoarthritis; MRI: magnetic resonance imaging; BML: bone marrow lesion.