RA characteristics between baseline and after 52 weeks (Wilcoxon signed-rank test).
| Characteristics | TCZ at Baseline | TCZ After 52 Weeks | p |
|---|---|---|---|
| Tender joint count | 6.25 ± 4.87 | 1.15 ± 1.76 | < 0.0001 |
| Swelling joint count | 5.20 ± 2.38 | 1.55 ± 2.11 | < 0.0001 |
| PtGAS | 55.00 ± 17.92 | 17.00 ± 15.25 | < 0.0001 |
| PGA | 57.25 ± 24.25 | 12.00 ± 12.81 | < 0.0001 |
| DAS28 | 5.18 ± 1.03 | 2.08 ± 0.73 | < 0.0001 |
| SDAI | 23.55 ± 6.76 | 5.67 ± 5.07 | < 0.0001 |
| CDAI | 21.90 ± 6.69 | 5.55 ± 5.06 | < 0.0001 |
| mHAQ | 0.57 ± 0.52 | 0.36 ± 0.48 | 0.0430 |
| CRP | 2.28 ± 2.74 | 0.05 ± 0.11 | < 0.0001 |
| ESR | 48.75 ± 30.61 | 5.85 ± 3.44 | < 0.0001 |
| MMP-3 | 314.66 ± 386.25 | 151.07 ± 237.53 | < 0.0001 |
RA: rheumatoid arthritis; PtGAS: patient global assessment; PGA: physician’s global assessment; DAS28: 28-joint Disease Activity Score; SDAI: Simple Disease Activity Index; CDAI: Clinical Disease Activity Index; mHAQ: modified Health Assessment Questionnaire; CRP: C–reactive protein; ESR: erythrocyte sedimentation rate; MMP-3: matrix metalloproteinase 3.