Table 4.

Subgroup analysis on recurrence of pseudo-obstruction. SSc disease characteristics are based on the Medsger severity scale classification12. Data in bold face are statistically significant.

DemographicsSingle Episode (%), n = 27 PatientsRecurrent Episode (%), n = 10 Patientsp
  Sex7 male0 male0.011
  Age61.1 ± 13.958.6 ± 9.90.467
  Race12 AA, 15 W2 AA, 8 W0.26
Disease characteristicsCases, n = 27Cases, n = 37
  Raynaud phenomenon20 (74)20 (54)0.123
  Digital ulcers8 (30)7 (19)0.37
  Interstitial lung disease7 (26)10 (27)1
  Pulmonary arterial hypertension8 (30)18 (49)0.197
  Esophageal involvement25 (93)21 (57)0.001
  Gastric involvement6 (22)14 (38)0.28
  Bacterial overgrowth3 (11)7 (19)0.49
  Cardiac involvement3 (11)7 (19)0.49
  MSK involvement10 (37)2 (5)0.002
  Renal involvement1 (4)0 (0)0.42
  Opioids (at admission)8 (30)3 (8)0.04
  Promotility (at admission)9 (33)22 (59)0.04
Symptoms
  Diarrhea7 (26)2 (5)0.02
  Abdominal pain17 (63)15 (41)0.12
  Nausea14 (52)35 (95)0.00008
  Weight loss8 (30)3 (8)0.04
  Hematochezia2 (7)0 (0)0.174
  Melena0 (0)2 (5)0.5
  Fever2 (7)2 (5)1
Treatment modality
  NPO21 (78)25 (71)0.77
  Surgery4 (15)2 (6)0.38
  Nasogastric tube10 (37)19 (54)0.2
  Prokinetic10 (37)21 (60)0.12
  Antibiotics11 (41)9 (26)0.27
  Intravenous fluids18 (67)23 (66)0.22
  Total parenteral nutrition7 (26)19 (54)0.03
Outcome
  Spontaneous resolution17 (63)28 (80)0.16
  Prolonged TPN1 (4)15 (43)0.0008
  Death5 (19)1 (3)0.077
  Days hospitalized15 ± 159 ± 90.06
  • SSc: systemic sclerosis; AA: African American; W: white; NPO: nil per os; TPN: total parenteral nutrition; MSK: musculoskeletal.