Associations of serum urate concentrations (mean ± SD) with SNP in the study population [healthy controls (n = 300) and patients with primary gout (n = 101)]. The number of study participants is provided in parentheses. p = Bonferroni test. Numbers in bold face are significant data.
| SNP Identified (Allele 1/Allele 2); Gene | Yes, Examined Allele* | No, Examined Allele | p |
|---|---|---|---|
| rs11231825 (C/T); URAT1 examined allele T | 5.34 ± 2.23 (187) | 4.79 ± 2.10 (213) | 0.0121 |
| rs16890979 (G/A); SLC2A9 examined allele A | 4.89 ± 2.02 (151) | 5.20 ± 2.27 (250) | 0.1749 |
| rs16890979 (G/A); SLC2A9 examined allele G | 5.13 ± 2.21 (386) | 3.87 ± 0.88 (15) | 0.0290 |
| rs17300741(G/A); OAT4 examined allele A | 5.14 ± 2.23 (296) | 4.71 ± 1.91 (97) | 0.0873 |
| rs1165196 (T/C); NPT1 examined allele C | 4.96 ± 2.09 (266) | 5.39 ± 2.35 (132) | 0.0630 |
| rs2231142 (C/A); ABCG2 examined allele A | 6.09 ± 2.56 (54) | 4.92 ± 2.08 (347) | 0.0003 |
↵* Both heterozygous and homozygous. SNP: single-nucleotide polymorphism.