Swollen and tender joint counts for the 4 cohorts of patients who met the ACR/EULAR 2010 RA criteria at baseline.
| Cohort 1, 1990–1994, n = 614 | Cohort 2, 1995–1999, n = 456 | Cohort 3, 2000–2004, n = 347 | Cohort 4, 2005–2008, n = 307 | p* | |||||
|---|---|---|---|---|---|---|---|---|---|
| Swollen joints, 28, median [IQR] | 614/614 | 9 [4, 14] | 456/456 | 7 [2, 12] | 347/347 | 5 [2, 10] | 307/307 | 4 [2, 8] | < 0.001 |
| Tender joints, 28, median [IQR] | 614/614 | 10 [4, 16] | 456/456 | 8 [3, 15] | 347/347 | 6 [2, 14] | 307/307 | 7 [2, 13] | < 0.001 |
| Swollen and tender, 28, median [IQR] | 614/614 | 5 [1, 10] | 456/456 | 3 [0, 8] | 347/347 | 2 [0, 5] | 307/307 | 2 [0, 5] | < 0.001 |
↵* Statistical significance set at 0.05 level. ACR: American College of Rheumatology; EULAR: European League Against Rheumatism; RA: rheumatoid arthritis; IQR: interquartile range.