Characteristics of patients with Takayasu arteritis (TA) and controls.
| All TA, n = 68 | Active TA, n = 30 | Inactive TA, n = 38 | Controls, n = 90 | p | |
|---|---|---|---|---|---|
| Age, yrs | 36.4 ± 12.6 | 34.9 ± 12.9 | 37.6 ± 12.4 | 37.2 ± 5.7 | 0.448 |
| Female, n (%) | 62 (91.2) | 28 (93.3) | 34 (89.5) | 80 (88.9) | 0.780 |
| BMI, kg/m2 | 24.0 ± 2.8 | 23.8 ± 2.6 | 24.2 ± 2.9 | 23.9 ± 1.3 | 0.634 |
| Disease duration, yrs | 9.3 ± 9.3 | 7.2 ± 8.9 | 11.0 ± 9.4 | – | 0.070 |
| Hypertension, n (%) | 43 (63.2) | 21 (70.0) | 22 (57.9) | – | 0.304 |
| Diabetes mellitus, n (%) | 3 (4.4) | 2 (6.7) | 1 (2.6) | – | 0.579 |
| Hyperlipidemia, n (%) | 13 (19.1) | 9 (30.0) | 5 (13.2) | – | 0.088 |
| ESR, mm/h | 17.7 ± 18.1 | 29.1 ± 22.0 # | 8.7 ± 4.9 | – | < 0.001 |
| CRP, mg/l | 5.0 ± 4.8 | 8.5 ± 5.0*# | 2.3 ± 2.4 | 1.4 ± 1.4 | < 0.001 |
| Creatine, mg/dl | 0.70 ± 0.16 | 0.71 ± 0.16 | 0.70 ± 0.15 | 0.71 ± 0.13 | 0.917 |
| WBC counts, ×109/l | 8.1 ± 2.7 | 8.9 ± 2.5*# | 7.4 ± 2.7* | 6.0 ± 1.3 | < 0.001 |
| NT-proBNP, pmol/l | 749.2 ± 318.3 | 915.0 ± 328.0*# | 618.2 ± 243.4* | 427.2 ± 81.4 | < 0.001 |
| LVEDD, mm | 45.9 ± 3.1 | 46.4 ± 2.4 | 45.6 ± 3.5 | 45.2 ± 3.4 | 0.209 |
| LVEF, % | 66.4 ± 4.6 | 66.1 ± 2.9 | 66.6 ± 5.6 | 66.2 ± 5.0 | 0.893 |
| Clinical classification, n (%) | |||||
| No vascular impairment | 1 (1.5) | 0 (0) | 1 (2.6) | – | |
| Type I | 22 (32.4) | 7 (23.3) | 15 (39.5) | – | |
| Type II | 18 (26.5) | 9 (30.0) | 9 (23.7) | – | |
| Type III | 26 (38.2) | 13 (43.3) | 13 (34.2) | – | |
| Type IV | 1 (1.5) | 1 (3.3) | 0 (0) | – | |
| Type I + IV | 2 (2.9) | 2 (6.7) | 0 (0) | – | |
| Type III + IV | 7 (10.3) | 4 (13.3) # | 3 (7.9) | – | |
| Prednisone, n (%) | 56 (82.4) | 28 (93.3) # | 27 (71.1) | – | 0.02 |
| Daily prednisone dose, mg | 18.9 ± 8.8 | 25.9 ± 5.8 | 11.5 ± 4.3 | – | < 0.001 |
Data are mean ± SD or number (%).
↵* p < 0.05 vs controls;
↵# p < 0.05 vs inactive TA. BMI: body mass index; ESR: erythrocyte sedimentation rate; CRP, C-reactive protein; WBC: white blood cell; NT-proBNP: N-terminal pro-brain natriuretic peptide; LVEDD: left ventricular end-diastolic diameter; LVEF: left ventricular ejection fraction.